Agentic engineering is a structured methodology for building AI-assisted software that actually reaches production, contrasted with vibe coding which produces demos that stall. The core framework has four pillars: spec-first design (writing a detailed specification before any prompt), the Ralph loop (an 8-step structured prompt cycle covering audit, planning, self-critique, test-first development, implementation, diagnosis, production readiness review, and iteration), layered testing (unit, integration, and end-to-end), and cross-model validation. Code generation is explicitly step 5 of 8, emphasizing that human thinking and verification are the highest-leverage activities. The approach is especially relevant for data scientists in regulated industries like life sciences and financial services where prototypes must meet audit and compliance requirements.