Post-quantum cryptography is essential for securing AI orchestration systems as quantum computers threaten current RSA and ECC encryption. The Model Context Protocol (MCP), which connects AI models to data sources, faces risks from "harvest now, decrypt later" attacks and puppet attacks via indirect prompt injection. Lattice-based encryption provides quantum resistance but complicates traditional deep packet inspection, requiring AI-powered anomaly detection using autoencoders to monitor metadata patterns. A 4D security framework (Identity, Intent, Resource, Environment) combined with Zero Trust architecture, hardware-backed keys, and differential privacy techniques creates defense-in-depth for AI infrastructure against both current and future quantum threats.