--- title: Atlas of the brain’s striatum could guide researchers to... description: MIT researchers built a new atlas of the brain's striatum using single-cell RNA sequencing and spatial transcriptomics, identifying 31 neuron subgroups based... canonical: https://daily.dev/posts/atlas-of-the-brain-s-striatum-could-guide-researchers-to-new-drug-treatments-dcuedxcwn twitter:card: summary_large_image twitter:site: @dailydotdev og:type: website og:site_name: daily.dev og:title: Atlas of the brain’s striatum could guide researchers to new drug treatments | daily.dev og:description: MIT researchers built a new atlas of the brain's striatum using single-cell RNA sequencing and spatial transcriptomics, identifying 31 neuron subgroups based... og:url: https://daily.dev/posts/atlas-of-the-brain-s-striatum-could-guide-researchers-to-new-drug-treatments-dcuedxcwn og:image: https://api.daily.dev/og/posts/DcUeDxcwN.png og:image:alt: Atlas of the brain’s striatum could guide researchers to new drug treatments og:image:width: 1200 og:image:height: 630 og:locale: en --- > ## Documentation Index > Fetch the complete documentation index at: https://daily.dev/llms.txt > Use this file to discover all available pages before exploring further. # Atlas of the brain’s striatum could guide researchers to new drug treatments **[MIT News](https://daily.dev/sources/mit)** · 6 min read · 0 upvotes · 0 comments ## Summary MIT researchers built a new atlas of the brain's striatum using single-cell RNA sequencing and spatial transcriptomics, identifying 31 neuron subgroups based on gene expression. The work reveals why dorsal striatal neurons are more vulnerable to Huntington's disease, identifies neuron populations linked to addiction, depression, and schizophrenia, and shows species differences between human and mouse opioid receptor expression that could improve substance use disorder models. The study, led by Myriam Heiman, Manolis Kellis, and Dana Gabuzda, appears in Cell. ## Full article daily.dev links to this article rather than hosting it. 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