AWS HealthOmics now supports ephemeral storage for private workflow tasks, providing dedicated scratch space mounted at /tmp. Each task gets 16 GiB by default at no extra cost, configurable up to 3,072 GiB per task via WDL, Nextflow, or CWL directives or the StartRun API. This benefits I/O-heavy bioinformatics workloads like genomic sequence alignment, BAM sorting, and variant calling by isolating scratch I/O from shared run storage. All ephemeral volumes are encrypted and automatically deleted on task termination. The feature is available across all regions where HealthOmics operates.

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