--- title: Biohub: The Future of Biology is Open-Source with Mark... description: Mark Zuckerberg, Priscilla Chan, and Alex Rives discuss the Chan Zuckerberg Biohub's $500M Virtual Biology Initiative, which aims to build hierarchical AI... canonical: https://daily.dev/posts/biohub-the-future-of-biology-is-open-source-with-mark-zuckerberg-priscilla-chan-and-alex-rives-i2wkf8us9 twitter:card: summary_large_image twitter:site: @dailydotdev og:type: website og:site_name: daily.dev og:title: Biohub: The Future of Biology is Open-Source with Mark Zuckerberg, Priscilla Chan, and Alex Rives | daily.dev og:description: Mark Zuckerberg, Priscilla Chan, and Alex Rives discuss the Chan Zuckerberg Biohub's $500M Virtual Biology Initiative, which aims to build hierarchical AI... og:url: https://daily.dev/posts/biohub-the-future-of-biology-is-open-source-with-mark-zuckerberg-priscilla-chan-and-alex-rives-i2wkf8us9 og:image: https://api.daily.dev/og/posts/i2WkF8uS9.png og:image:alt: Biohub: The Future of Biology is Open-Source with Mark Zuckerberg, Priscilla Chan, and Alex Rives og:image:width: 1200 og:image:height: 630 og:locale: en --- > ## Documentation Index > Fetch the complete documentation index at: https://daily.dev/llms.txt > Use this file to discover all available pages before exploring further. # Biohub: The Future of Biology is Open-Source with Mark Zuckerberg, Priscilla Chan, and Alex Rives **[No Priors: AI, Machine Learning, Tech, & Startups](https://daily.dev/sources/nopriorspodcast)** · 56 min read · 0 upvotes · 0 comments ## Summary Mark Zuckerberg, Priscilla Chan, and Alex Rives discuss the Chan Zuckerberg Biohub's $500M Virtual Biology Initiative, which aims to build hierarchical AI world models of biological systems — from proteins to cells to whole organisms. The effort combines frontier AI research with frontier biology (wet labs, imaging, cellular engineering) to generate novel datasets unavailable on the internet. A key recent milestone is the new ESMfold model, which folded over 1.1 billion proteins and enables digital design of single-chain antibodies with nanomolar binding affinity. All tools are released as open source to accelerate the broader scientific community. The long-term vision is personalized medicine: understanding individual genetics, disease mechanisms, and designing bespoke protein therapeutics. The nonprofit model is chosen deliberately to maximize scientific reach and avoid commercial constraints on a 10–15 year research horizon. ## Full article daily.dev links to this article rather than hosting it. Read it at the original source: ## Similar posts on daily.dev - [How Open Science Can Help Researchers Prepare for the Next Pandemic](https://daily.dev/posts/how-open-science-can-help-researchers-prepare-for-the-next-pandemic-j2nxjuah9) · NVIDIA · 0 upvotes · 0 comments - [MIT scientists debut a generative AI model that could create molecules addressing hard-to-treat diseases](https://daily.dev/posts/mit-scientists-debut-a-generative-ai-model-that-could-create-molecules-addressing-hard-to-treat-dise-ugenvnhjv) · MIT News · 0 upvotes · 0 comments - [Astromech raised $20mn at $3.8bn to forecast how biology breaks](https://daily.dev/posts/astromech-raised-20mn-at-3-8bn-to-forecast-how-biology-breaks-bt0so2z4q) · The Next Web · 0 upvotes · 0 comments - [How AI helps scientists design the next generation of medicines](https://daily.dev/posts/how-ai-helps-scientists-design-the-next-generation-of-medicines-rsdf6xsgg) · MIT Technology Review · 0 upvotes · 0 comments --- Tags: [#open-source](https://daily.dev/tags/open-source), [#biotech](https://daily.dev/tags/biotech) [View this post on daily.dev](https://daily.dev/posts/biohub-the-future-of-biology-is-open-source-with-mark-zuckerberg-priscilla-chan-and-alex-rives-i2wkf8us9) ```json {"@context":"https://schema.org","@graph":[{"@type":"Organization","@id":"https://daily.dev/#organization","name":"daily.dev","url":"https://daily.dev","logo":{"@type":"ImageObject","url":"https://daily.dev/apple-touch-icon.png","width":180,"height":180},"sameAs":["https://twitter.com/dailydotdev","https://github.com/dailydotdev","https://www.linkedin.com/company/daily-dev-ltd"]},{"@type":"WebSite","@id":"https://daily.dev/#website","url":"https://daily.dev","name":"daily.dev","publisher":{"@id":"https://daily.dev/#organization"},"potentialAction":{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://daily.dev/search?q={search_term_string}"},"query-input":"required name=search_term_string"}}]} {"@context":"https://schema.org","@type":"TechArticle","headline":"Biohub: The Future of Biology is Open-Source with Mark Zuckerberg, Priscilla Chan, and Alex Rives","url":"https://daily.dev/posts/biohub-the-future-of-biology-is-open-source-with-mark-zuckerberg-priscilla-chan-and-alex-rives-i2wkf8us9","mainEntityOfPage":{"@type":"WebPage","@id":"https://daily.dev/posts/biohub-the-future-of-biology-is-open-source-with-mark-zuckerberg-priscilla-chan-and-alex-rives-i2wkf8us9"},"datePublished":"2026-06-10T13:23:45.421Z","dateModified":"2026-06-10T13:24:09.407Z","description":"Mark Zuckerberg, Priscilla Chan, and Alex Rives discuss the Chan Zuckerberg Biohub's $500M Virtual Biology Initiative, which aims to build hierarchical AI...","image":"https://i.ytimg.com/vi/u8cYwaLzN-k/sddefault.jpg","thumbnailUrl":"https://i.ytimg.com/vi/u8cYwaLzN-k/sddefault.jpg","isAccessibleForFree":true,"articleSection":"No Priors: AI, Machine Learning, Tech, & Startups","inLanguage":"en","publisher":{"@type":"Organization","name":"daily.dev","url":"https://daily.dev","logo":{"@type":"ImageObject","url":"https://daily.dev/apple-touch-icon.png","width":180,"height":180}},"author":{"@type":"Organization","name":"No Priors: AI, Machine Learning, Tech, & Startups","logo":"https://media.daily.dev/image/upload/s--Hj2kMkm_--/f_auto,q_auto/v1772391934/logos/nopriorspodcast","url":"https://daily.dev/sources/nopriorspodcast"},"commentCount":0,"discussionUrl":"https://daily.dev/posts/biohub-the-future-of-biology-is-open-source-with-mark-zuckerberg-priscilla-chan-and-alex-rives-i2wkf8us9","interactionStatistic":[{"@type":"InteractionCounter","interactionType":{"@type":"LikeAction"},"userInteractionCount":0},{"@type":"InteractionCounter","interactionType":{"@type":"CommentAction"},"userInteractionCount":0}],"keywords":"open-source,biotech","timeRequired":"PT56M","video":{"@type":"VideoObject","name":"Biohub: The Future of Biology is Open-Source with Mark Zuckerberg, Priscilla Chan, and Alex Rives","description":"Mark Zuckerberg, Priscilla Chan, and Alex Rives discuss the Chan Zuckerberg Biohub's $500M Virtual Biology Initiative, which aims to build hierarchical AI...","thumbnailUrl":"https://i.ytimg.com/vi/u8cYwaLzN-k/sddefault.jpg","uploadDate":"2026-06-10T13:23:45.421Z","duration":"PT56M","url":"https://api.daily.dev/r/i2WkF8uS9","embedUrl":"https://www.youtube.com/embed/u8cYwaLzN-k"}} {"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://daily.dev"},{"@type":"ListItem","position":2,"name":"No Priors: AI, Machine Learning, Tech, & Startups","item":"https://daily.dev/sources/nopriorspodcast"},{"@type":"ListItem","position":3,"name":"Biohub: The Future of Biology is Open-Source with Mark Zuckerberg, Priscilla Chan, and Alex Rives"}]} ```