The Agent-to-Agent (A2A) protocol, now one year old, enables AI agents to collaborate and hand off tasks securely rather than operating as isolated, stateless tools. Unlike REST APIs, A2A is designed for fluid, autonomous agent interactions. A real-world example is FoldRun, an agentic interface for protein structure prediction that integrates with Gemini Enterprise and Gemini CLI, dynamically choosing between models like AlphaFold 2, OpenFold 3, and Boltz-2. The protocol is gaining traction across industries, with official SDKs available to help developers join the ecosystem.
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Beyond Tools: The Rise of the Agentic EcosystemSpotlight: FoldRun—Science at Scale Without the Stack566 Impressions