--- title: How The Vagus Nerve Promotes Healthy Cognition Via... description: New research in rat models shows the vagus nerve plays a key role in cognitive function by triggering acetylcholine release from medial septum neurons during... canonical: https://daily.dev/posts/how-the-vagus-nerve-promotes-healthy-cognition-via-acetylcholine-signaling-kuhpyxp3f twitter:card: summary_large_image twitter:site: @dailydotdev og:type: website og:site_name: daily.dev og:title: How The Vagus Nerve Promotes Healthy Cognition Via Acetylcholine Signaling | daily.dev og:description: New research in rat models shows the vagus nerve plays a key role in cognitive function by triggering acetylcholine release from medial septum neurons during... og:url: https://daily.dev/posts/how-the-vagus-nerve-promotes-healthy-cognition-via-acetylcholine-signaling-kuhpyxp3f og:image: https://api.daily.dev/og/posts/kuHPyXP3f.png og:image:alt: How The Vagus Nerve Promotes Healthy Cognition Via Acetylcholine Signaling og:image:width: 1200 og:image:height: 630 og:locale: en --- > ## Documentation Index > Fetch the complete documentation index at: https://daily.dev/llms.txt > Use this file to discover all available pages before exploring further. # How The Vagus Nerve Promotes Healthy Cognition Via Acetylcholine Signaling **[Hackaday](https://daily.dev/sources/hackaday)** · 2 min read · 0 upvotes · 0 comments ## Summary New research in rat models shows the vagus nerve plays a key role in cognitive function by triggering acetylcholine release from medial septum neurons during eating. Disrupting this gut-brain signaling pathway impairs memory and attention. The findings also link early-life Western diets (high fat and sugar) to cognitive decline by disrupting this acetylcholine regulation mechanism, with implications for understanding Alzheimer's and dementia. ## Full article daily.dev links to this article rather than hosting it. 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