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description: MIT researchers built an implantable device called LUCID that uses ultrasound to improve drug delivery to the brain after glioblastoma surgery. The device...
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og:description: MIT researchers built an implantable device called LUCID that uses ultrasound to improve drug delivery to the brain after glioblastoma surgery. The device...
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# Implantable device uses ultrasound to improve drug delivery to the brain

**[MIT News](https://daily.dev/sources/mit)** · 5 min read · 0 upvotes · 0 comments

## Summary

MIT researchers built an implantable device called LUCID that uses ultrasound to improve drug delivery to the brain after glioblastoma surgery. The device combines a drug-delivery cannula 3D-printed onto an array of 24 miniature ultrasound transducers, which help drug molecules spread farther. Its reservoir holds about 100 microliters of fluid, delivered via a passive osmotic pump, while ultrasound is controlled wirelessly through Bluetooth and powered by a wirelessly rechargeable battery. In tissue phantoms and a mouse study, ultrasound-aided delivery spread drug molecules and an MRI contrast agent farther than delivery without ultrasound. The technology could potentially be used for immunotherapies, gene therapies, and other soft tissues beyond the brain.

## Full article

daily.dev links to this article rather than hosting it. Read it at the original source: <https://news.mit.edu/2026/implantable-device-uses-ultrasound-improve-drug-delivery-brain-1026>

## Questions this post answers

### How does the LUCID device use ultrasound to improve brain drug delivery after glioblastoma surgery?

LUCID is an implantable device from MIT that 3D-prints a drug-delivery cannula directly onto an array of 24 miniature ultrasound transducers. The transducers generate ultrasound waves at the needle tip, creating convective flows and temporarily increasing blood-brain barrier permeability so drug molecules spread farther into surrounding tissue, even during slow infusion.

_Anyone tracking advances in implantable drug delivery can follow this research on daily.dev._

### How much fluid can the LUCID brain implant hold and how is it powered?

The implant's reservoir carries about 100 microliters of fluid, delivered through a passive osmotic pump. Ultrasound dosing is controlled wirelessly via Bluetooth, and the device includes a small battery that can be recharged wirelessly, allowing doctors to program infusion size, length, and number of doses after implantation.

_Readers following medical device engineering details can keep up with this kind of research on daily.dev._

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