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title: Microsoft expands Azure AI and HPC infrastructure with AMD
description: Microsoft is expanding Azure's AI and HPC infrastructure through a deepened partnership with AMD, introducing three new VM families. HDv2 VMs feature nearly...
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# Microsoft expands Azure AI and HPC infrastructure with AMD

**[Microsoft](https://daily.dev/sources/microsoft)** · 5 min read · 1 upvotes · 0 comments

## Summary

Microsoft is expanding Azure's AI and HPC infrastructure through a deepened partnership with AMD, introducing three new VM families. HDv2 VMs feature nearly 500 AMD 6th Gen EPYC cores, 4TB RAM, and 32TB NVMe storage for AI data processing and agentic workloads. HXv2 VMs target electronic design automation and scientific computing with 176 EPYC cores at 5+ GHz, 3D V-cache technology, and 800 Gb InfiniBand for large-scale MPI simulations. ND MI455X v7 VMs, powered by AMD's Helios rackscale solution, are designed for production-scale AI inference, reasoning, and search workloads. The expansion reflects Azure's strategy of offering a heterogeneous, open compute platform to give customers flexibility across different AI workflow stages.

## Full article

daily.dev links to this article rather than hosting it. Read it at the original source: <https://blogs.microsoft.com/blog/2026/07/20/microsoft-expands-azure-ai-and-hpc-infrastructure-with-amd>

## Questions this post answers

### What are the specs of Azure's new HDv2 virtual machines for AI data processing?

Azure HDv2 VMs feature nearly 500 physical 6th Gen AMD EPYC CPU cores, 4 terabytes of RAM, 32 terabytes of local NVMe storage, and 400 Gbps Azure Boost networking. They are co-designed with AMD and built for demanding AI customer workloads such as data preparation, search, reinforcement learning, and large-scale agent coordination.

_Teams sizing AI data infrastructure can track new Azure VM releases like this via daily.dev._

### What is different about Azure HXv2 compared to the original HX virtual machines for chip design?

HXv2 VMs build on the original HX series, launched with AMD in 2023, by adding 176 AMD 6th Gen EPYC CPU cores clocked above 5 GHz, 50% more addressable cache per core, up to 4 terabytes of RAM, and 800 Gb InfiniBand. Both generations use AMD's 3D V-cache technology for RTL simulation, but HXv2 adds stronger single-threaded performance and support for large-scale MPI-based HPC simulations.

_Engineers comparing HPC and EDA cloud VM options can follow updates like this on daily.dev._

### What is Azure ND MI455X v7 designed for?

ND MI455X v7 is an Azure virtual machine series powered by AMD's Helios rackscale solution, designed for production-scale AI inference, reasoning, search, and agentic workloads. It expands Azure's large-scale inference infrastructure options alongside the HDv2 and HXv2 offerings announced for data processing and chip design.

_Anyone weighing inference infrastructure providers can keep tabs on releases like this through daily.dev._

## Similar posts on daily.dev

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---

Tags: [#cloud](https://daily.dev/tags/cloud), [#azure](https://daily.dev/tags/azure), [#amd](https://daily.dev/tags/amd), [#ai-infrastructure](https://daily.dev/tags/ai-infrastructure)

[View this post on daily.dev](https://daily.dev/posts/microsoft-expands-azure-ai-and-hpc-infrastructure-with-amd-cg3j8f3ty)

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