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title: New Drug Hopes To Treat Sleep Apnea Without Masks
description: Sleep apnea causes repeated breathing cessation during sleep due to throat muscle relaxation. Traditional CPAP machines are effective but have poor patient...
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# New Drug Hopes To Treat Sleep Apnea Without Masks

**[Hackaday](https://daily.dev/sources/hackaday)** · 4 min read · 0 upvotes · 0 comments

## Summary

Sleep apnea causes repeated breathing cessation during sleep due to throat muscle relaxation. Traditional CPAP machines are effective but have poor patient compliance, with up to 50% abandoning treatment within a year. A new drug combination called AD109 targets the neuromuscular causes directly using aroxybutynin and atomoxetine to maintain upper airway muscle tone. Phase 2 trials showed a 45% reduction in breathing disruptions, though side effects include dry mouth, urinary hesitancy, and insomnia. Phase 3 trials are ongoing to test efficacy across severity levels before potential commercialization.

## Full article

daily.dev links to this article rather than hosting it. Read it at the original source: <https://hackaday.com/2026/01/22/new-drug-hopes-to-treat-sleep-apnea-without-masks/>

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---

Tags: [#healthcare](https://daily.dev/tags/healthcare), [#biotech](https://daily.dev/tags/biotech)

[View this post on daily.dev](https://daily.dev/posts/new-drug-hopes-to-treat-sleep-apnea-without-masks-oezxqdize)

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