---
title: "RoboChem Flex: democratisation of the autonomous synthesis robot"
url: https://daily.dev/posts/robochem-flex-democratisation-of-the-autonomous-synthesis-robot-j1ouznnbp
source_url: https://robohub.org/robochem-flex-democratisation-of-the-autonomous-synthesis-robot
type: article
source: "Robohub"
published: 2026-06-02T10:53:01.138Z
updated: 2026-06-02T10:53:29.350Z
tags: ["machine-learning", "open-source", "data-science", "robotics"]
reading_time: 4
upvotes: 0
comments: 0
language: en
---

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# RoboChem Flex: democratisation of the autonomous synthesis robot

**[Robohub](https://daily.dev/sources/robohub)** · 4 min read · 0 upvotes · 0 comments

## Summary

Researchers at the University of Amsterdam have developed RoboChem Flex, a low-cost autonomous synthesis robot designed to democratize AI-powered chemical synthesis optimization. The system costs approximately $5,000 — a 10x reduction from the original $50,000+ RoboChem — and uses 3D-printed components, off-the-shelf hardware, and an open-source control package called OmniPlatypus. It features a modular Bayesian Optimization AI agent and supports inline analytics (NMR, UHPLC-MS, Raman) for fully autonomous closed-loop operation, or a human-in-the-loop sampling approach for labs with limited budgets. The design has been validated across six case studies covering photocatalysis, biocatalysis, and thermal cross-coupling. All code, firmware, 3D printing files, and schematics are openly available on GitHub, enabling any lab worldwide to build their own system.

## Full article

daily.dev links to this article rather than hosting it. Read it at the original source: <https://robohub.org/robochem-flex-democratisation-of-the-autonomous-synthesis-robot>

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---

Tags: [#machine-learning](https://daily.dev/tags/machine-learning), [#open-source](https://daily.dev/tags/open-source), [#data-science](https://daily.dev/tags/data-science), [#robotics](https://daily.dev/tags/robotics)

[View this post on daily.dev](https://daily.dev/posts/robochem-flex-democratisation-of-the-autonomous-synthesis-robot-j1ouznnbp)