The EyeDropper API, available in Chromium 95+, lets websites allow users to pick colors from anywhere on their screen with just a few lines of JavaScript. The API exposes a global `EyeDropper` object with an `open()` method that returns a promise resolving to a `ColorSelectionResult` containing the picked color as an sRGB hex value. Key constraints include requiring a user-initiated event to open the picker (for security), and colors being captured as a static screenshot rather than live screen data. Current limitations include no live color preview while hovering, colors restricted to the sRGB color model (no wide-gamut P3 support), and no native multi-color selection. The API is not yet supported in Firefox or Safari, and the author encourages developers to upvote the relevant browser issues.